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Contains natural-source GABA, a brain chemical to promote a calm state of mind and restful sleep.

PharmaGABA features a natural source of the inhibitory neurotransmitter – GABA. GABA supports restful sleep, acts like a "brake" on stress, and provides a focused state of mind.


How to use

Take 1 capsule one to three times daily or as recommended by your health professional.

Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 60
Expiry Date: 31 August 2025

Key Ingredients

  • Gamma-Aminobutyric Acid [GABA] (250mg)

Other Ingredients: Calcium Laurate, Hypromellose Capsule, Magnesium (Citrate), Microcrystalline Cellulose.


Allergy Warning
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Pregnancy Warning
If pregnant, nursing, or trying to conceive do not use this product.

There are no known adverse interactions or contraindications at publication date.


Gamma-aminobutyric acid (GABA) is a major calming brain chemical or neurotransmitter.* Clinical studies show that the natural form of GABA that is in Thorne's PharmaGABA can decrease the brain's stress-related beta waves and increase the production of its alpha-waves, creating a profound sense of physical relaxation while maintaining mental focus.* Other studies have shown reduced pupil diameter, heart rate, and two natural biomarkers of stress – salivary cortisol and chromogranin A – all signs of relaxation.* In addition, studies also indicate GABA can enhance sleep.* In a head-to-head, double-blind trial of natural PharmaGABA versus synthetic GABA, the synthetic GABA did not demonstrate these positive effects.* PharmaGABA-250 offers 250 mg of natural GABA per capsule, while PharmaGABA-100 offers 100 mg per capsule. Both are non-habit forming.

In a recent study of the effect of nutrient supplementation on muscle mass, 21 males, average age 39, who did not exercise regularly, were given 10 grams of whey protein or 10 grams of whey protein plus 100 mg of PharmaGABA daily for 12 weeks. Both groups participated in twice weekly 60-minute strength training sessions that consisted of leg presses, leg extensions, leg curls, chest presses, and pull-downs. Total body lean muscle mass increased significantly in the whey protein-plus-PharmaGABA group compared to the whey-only group.*

The natural GABA in Thorne's PharmaGABA suite is produced via a fermentation process that utilizes Lactobacillus hilgardii, the same bacteria that is used to ferment cabbage in the preparation of the traditional Korean dish known as kimchi.

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Customer Reviews

Based on 18 reviews
Ryan N.
Great for quieting the brain before sleep

I have trouble turning off before sleep. Diving into various reasons why this could be, I went down the rabbit hole of learning about glutamate and GABA. Since I am “on” all the time, I am guessing I have trouble converting glutamate to GABA. Supplementing with GABA before sleep has been a real game changer for me, and I will continue to make it part of my nightly routine.



Justin C.

Perfect to take with dinner to calm the mind and be ready for bed soon after.

Kaiser A.
Good product

As a grad student, I am chronically stressed; this helps relieve some of that stress.

Cheyenne E.
Great for sleep

With PharmaGABA, I find myself falling asleep much easier and staying asleep. I feel much more rested the next day when I take PharmaGABA before bed.