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Supports your gut barrier and eases the symptoms of leaky gut or IBS (Irritable Bowel Syndrome).

Perma-Clear® supports a healthy intestinal lining and promotes beneficial gut flora. It supports immune function in the gut and provides nutritional support for "leaky gut" syndrome.


How to use

Take 3 capsules two times daily or as recommended by your health professional.

Supplement Facts

Serving Size: 3 Capsules
Servings Per Container: 60
Expiry Date: 13 October 2024

Key Ingredients

  • Bacillus Coagulans (75mg)
  • Ginger Extract [Zingiber Officinale] (30mg)
  • L-Glutamine (900mg)
  • N-Acetylglucosamine (750mg)
  • Quercetin Phytosome (112.5mg)
  • Saccharomyces Boulardii (112.5mg)

Other Ingredients: Calcium Laurate, Hypromellose Capsule, Microcrystalline Cellulose, Silicon Dioxide.


Allergy Warning
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

If pregnant, consult your health professional before using this product.

Because of the blood-thinning effects of ginger, Perma-Clear® should be used with caution or avoided in an individual on anticoagulant therapy.

View full details
  • What is Leaky Gut?

    A condition in which the gut’s weakened mucosal barrier leads to symptoms such as diarrhea, cramps, nausea and more.

  • Support Your Gut Barrier

    Perma-Clear® nourishes, soothes and strengthens the intestinal lining and promotes normal gut permeability.

  • Keep Your Gut Healthy

    Promotes the growth of beneficial gut flora, antioxidant activity, and stimulates immune function in the gut.

Key Ingredients

The Good Stuff

Bacillus Coagulans

Bacillus coagulans (also known as Lactobacillus Sporogenes) is a lactic acid-producing bacteria that promotes GI function and bowel regularity. It is unique in probiotic supplementation because this beneficial bacteria is dormant in the bottle but reverts to a growing bacteria in the intestines. As a result, it resists being killed by stomach acid. In contrast, many Lactobacillus probiotics lose much of their potency before use and do not survive their transit through the stomach. Unlike many Lactobacillus probiotics, Bacillus Coagulans is heat stable and resistant to stomach acid.

Ginger Extract

Ginger (Zingiber Officinale) has been used for centuries as a folk remedy to alleviate nausea and soothe the GI tract. It is also used as a carminative, meaning it helps decrease gas production, and can also improve digestion by stimulating hydrochloric acid and bile.

One of the other ways ginger benefits the GI tract is by increasing the motility of the GI tract, which increases the rate the stomach empties. It encourages normal intestinal movement while inhibiting abnormal movements like GI tract spasms.

Several studies have also found that consuming ginger protects the stomach from ulcer-causing agents, such as aspirin, the anti-inflammatory drug indomethacin, and the bacteria Helicobacter Pylori.


Glutamine, the body’s most abundant amino acid, is used by skeletal muscles, the GI tract, kidneys, immune cells, and more. It is also the primary fuel source for enterocytes – the cells that make up the inner surface of the intestines.

Digesting food, absorbing nutrients, eliminating waste and resisting toxins, all result in considerable wear and tear, which is why significant nutrient support is required for these cells to regenerate every 4-5 days.

Increased exercise intensity can also cause the demand for glutamine by skeletal muscles to increase, decreasing the available glutamine in the body’s total amino acid pool and leaving the intestines and other glutamine-dependent tissues to compete for what remains.

L-Glutamine nourishes and soothes intestinal mucosal cells to heal and prevent conditions such as leaky gut syndrome.

N-Acetylglucosamine (NAG)

Promotes the gut's normal mucus layer and the growth of desirable Bifidobacterium Bifidum.

Quercetin Phytosome

An antioxidant flavonoid that supports balanced immune function, inflammatory response, and dampens histamine release.

Quercetin is a flavonoid found in many plant-based foods – onions having the highest amount. Other fruits and vegetables that contain significant amounts of quercetin include apples, berries, grapes, and green leafy vegetables. As ubiquitous as quercetin is in nature, it also has wide-ranging benefits in the body. One important actions is to strengthen mast cell membranes (a type of white blood cell), which down-regulates the release of histamine, providing nutritional support for skin sensitivity (like hives) and seasonal allergies. Quercetin also has important antioxidant activities and supports balanced immune function and inflammatory response – all of which provide benefit for respiratory health, athletic performance, healthy aging, and more.

New research is emerging that supports quercetin’s role in healthy aging. Quercetin is the first natural substance to be identified as a senolytic – a substance that clears worn out, dysfunctional cells (senescent cells) from the body. Senescent cells have been identified as a major contributor to the aging process.

Saccharomyces Boulardii

Found in lychee peel and mangosteens, Saccharomyces Boulardii is a yeast species that enhances immune function in the gut by increasing sIgA, the first-line defense immunoglobin of the gastrointestinal tract.

In addition to enhancing immune function in the gut, this yeast species also supports the growth of beneficial intestinal flora, and it can also be helpful for mitigating occasional diarrhea.

Quercetin Phytosome

The Thorne Difference

In its unbound form, quercetin is known for its poor absorption. The crucial advantage attributable to quercetin phytosome is that it’s made using advanced phytosome technology. Phytosome complexes are created by a patented process that binds a botanical constituent (in this case quercetin) to phospholipids that are key components of cell membranes. In the case of quercetin phytosome, the quercetin is combined with sunflower-sourced phospholipids, thus creating a phytosome complex that can easily cross the gut barrier. A recent study found up to 20-times greater blood levels of quercetin following ingestion of quercetin phytosome compared to unbound quercetin.

Customer Reviews

Based on 2 reviews
Richard B.
Gut Health

This finally cleared up my gut issues.

revekah e.
Game changer

I'm not sure how one is supposed to take this, but I take two capsules before I eat any high-volume meal (with lots of raw or cooked vegetables) or foods off my beaten path, and it really helps me digest. Otherwise, I have a lot of discomfort, bloating, nausea, and get completely constipated. I have been having these symptoms for about a year, and this is the first thing I've taken that actually moved the needle. It's expensive but makes you feel normal!